LGI1 抗体 (AA 35-557)
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Quick Overview for LGI1 抗体 (AA 35-557) (ABIN7874172)
抗原
See all LGI1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 35-557
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原理
- LGI1 Antibody / Leucine-rich glioma inactivated 1
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids K35-A557) was used as the immunogen for the LGI1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the LGI1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the LGI1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))
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别名
- LGI1
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背景
- Leucine-rich, glioma inactivated 1, also known as LGI1, is a protein which in humans is encoded by the LGI1 gene. This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants.
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UniProt
- O95970
抗原
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