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Vitamin D-Binding Protein 抗体 (AA 35-175)

This 小鼠 单克隆 antibody specifically detects Vitamin D-Binding Protein in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7874132
发货至: 中国
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Quick Overview for Vitamin D-Binding Protein 抗体 (AA 35-175) (ABIN7874132)

抗原

See all Vitamin D-Binding Protein (GC) 抗体
Vitamin D-Binding Protein (GC)

适用

  • 82
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  • 5
  • 5
  • 5
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  • 2
  • 1
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宿主

  • 80
  • 19
  • 2
  • 1
小鼠

克隆类型

  • 67
  • 35
单克隆

标记

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  • 15
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  • 3
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This Vitamin D-Binding Protein antibody is un-conjugated

应用范围

  • 67
  • 45
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  • 16
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  • 13
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  • 11
  • 4
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  • 1
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

VDBP-4482
  • 抗原表位

    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
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    • 1
    • 1
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    • 1
    AA 35-175

    原理

    Vitamin D binding protein Antibody / VDBP / GC (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A portion of amino acids 35-175 was used as the immunogen for the Vitamin D binding protein antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the Vitamin D binding protein antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the Vitamin D binding protein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Vitamin D-Binding Protein (GC)

    别名

    Vitamin D binding protein

    背景

    Vitamin D-binding protein (DBP) is a multi-functional serum protein that binds to the plasma membranes of numerous cell types and mediates a variety of cellular functions. The locus of the DBP protein (also known as group-specific component protein or GC) is located at human chromosome 4q13.3. DBP functions in organ-specific transportation of vitamin D and its metabolites to the various target organs of the vitamin D endocrine system. In addition, DBP has immunomodulatory properties and is able to bind to the surface of leukocytes. DBP binds to the plasma membrane through a chondroitin sulfate proteoglycan. DBP serves as a co-chemotactic factor for C5a to enhance the chemotactic activity of C5a. DBP can also bind to globular Actin with high affinity and is involved in the clearance of Actin from the blood. DBP plays an important role in osteoclast differentiation. The diverse cellular functions of DBP require its cell surface binding ability to mediate different biological processes.

    UniProt

    P02774

    途径

    Metabolism of Steroid Hormones and Vitamin D, Monocarboxylic Acid Catabolic Process
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