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ITGA8 抗体 (AA 347-964)

The 兔 多克隆 anti-ITGA8 antibody is suitable to detect ITGA8 in samples from 人. It has been validated for WB, ELISA, FACS 和 IF.
产品编号 ABIN7874121
发货至: 中国
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Quick Overview for ITGA8 抗体 (AA 347-964) (ABIN7874121)

抗原

See all ITGA8 抗体
ITGA8 (Integrin alpha-8 (ITGA8))

适用

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宿主

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克隆类型

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多克隆

标记

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This ITGA8 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)
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    AA 347-964

    原理

    Integrin alpha 8 Antibody / ITGA8

    纯化方法

    Antigen affinity purified

    免疫原

    E. coli-derived recombinant human protein (amino acids E347-D964) was used as the immunogen for the Integrin alpha 8 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Integrin alpha 8 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Integrin alpha 8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    ITGA8 (Integrin alpha-8 (ITGA8))

    别名

    Integrin alpha 8

    背景

    Integrin alpha-8 is a protein that in humans is encoded by the ITGA8 gene. Integrins are heterodimeric transmembrane receptor proteins that mediate numerous cellular processes including cell adhesion, cytoskeletal rearrangement, and activation of cell signaling pathways. Integrins are composed of alpha and beta subunits. This gene encodes the alpha 8 subunit of the heterodimeric integrin alpha8beta1 protein. The encoded protein is a single-pass type 1 membrane protein that contains multiple FG-GAP repeats. This repeat is predicted to fold into a beta propeller structure. This gene regulates the recruitment of mesenchymal cells into epithelial structures, mediates cell-cell interactions, and regulates neurite outgrowth of sensory and motor neurons. The integrin alpha8beta1 protein thus plays an important role in wound-healing and organogenesis. Mutations in this gene have been associated with renal hypodysplasia/aplasia-1 (RHDA1) and with several animal models of chronic kidney disease. Alternate splicing results in multiple transcript variants encoding distinct isoforms.

    UniProt

    P53708
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