ADRA2B 抗体 (AA 343-369)
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北京 101111
Quick Overview for ADRA2B 抗体 (AA 343-369) (ABIN7874107)
抗原
See all ADRA2B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 343-369
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原理
- Alpha-2B Adrenergic Receptor Antibody / ADRA2B
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 343-369 from the human protein was used as the immunogen for the Alpha-2B Adrenergic Receptor antibody.
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亚型
- IgG
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anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) (AA 343-369) antibody
ADRA2B 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB22486 unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) (2nd Extracellular Loop), (AA 160-174), (C169S) antibodyADRA2B 适用: 大鼠 WB, FACS, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) antibodyADRA2B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) (AA 349-378) antibodyADRA2B 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) (AA 343-369) antibodyADRA2B 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) antibodyADRA2B 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) antibodyADRA2B 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) (AA 1-100) antibodyADRA2B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Alpha-2B Adrenergic Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Alpha-2B Adrenergic Receptor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- ADRA2B (Adrenergic, alpha-2B-, Receptor (ADRA2B))
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别名
- Alpha-2B Adrenergic Receptor
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背景
- Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Alpha 2B adrenergic receptor subtype was observed to associate with eIF-2B, a guanine nucleotide exchange protein that functions in regulation of translation. A polymorphic variant of the alpha2B subtype, which lacks 3 glutamic acids from a glutamic acid repeat element, was identified to have decreased G protein-coupled receptor kinase-mediated phosphorylation and desensitization, this polymorphic form is also associated with reduced basal metabolic rate in obese subjects and may therefore contribute to the pathogenesis of obesity. Alpha 2B adrenergic receptor gene contains no introns in either its coding or untranslated sequences.
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UniProt
- P18089
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途径
- EGFR Signaling Pathway, cAMP Metabolic Process
抗原
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