GALNT14 抗体 (AA 34-639)
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Quick Overview for GALNT14 抗体 (AA 34-639) (ABIN7874091)
抗原
See all GALNT14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 34-639
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原理
- GALNT15 Antibody / Polypeptide N-acetylgalactosaminyltransferase 15
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纯化方法
- Immunogen affinity purified
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免疫原
- E.coli-derived human GALNT15 recombinant protein (Position: H34-R639) was used as the immunogen for the GALNT15 antibody.
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亚型
- IgG
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anti-UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 14 (GalNAc-T14) (GALNT14) (AA 494-551) antibody
GALNT14 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A8 unconjugated
anti-UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 14 (GalNAc-T14) (GALNT14) (AA 35-335) antibodyGALNT14 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 14 (GalNAc-T14) (GALNT14) (AA 1-552) antibodyGALNT14 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 14 (GalNAc-T14) (GALNT14) (AA 1-552) antibodyGALNT14 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 14 (GalNAc-T14) (GALNT14) (AA 323-372) antibodyGALNT14 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 14 (GalNAc-T14) (GALNT14) (AA 1-189) antibodyGALNT14 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 14 (GalNAc-T14) (GALNT14) (AA 39-66), (N-Term) antibodyGALNT14 适用: 人 WB 宿主: 兔 Polyclonal RB37322 unconjugated
anti-UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 14 (GalNAc-T14) (GALNT14) (Middle Region) antibodyGALNT14 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, 斑马鱼, Cow WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the GALNT15 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the GALNT15 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- GALNT14 (UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 14 (GalNAc-T14) (GALNT14))
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别名
- GALNT15
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背景
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GALNT15 antibody detects Polypeptide N-acetylgalactosaminyltransferase 15, encoded by the GALNT15 gene. Polypeptide N-acetylgalactosaminyltransferase 15 is a member of the GalNAc-transferase enzyme family that initiates O-linked glycosylation of proteins. GALNT15 antibody provides researchers with a specific reagent for studying protein glycosylation, cell surface biology, and disease mechanisms associated with altered glycan structures.
Polypeptide N-acetylgalactosaminyltransferase 15 catalyzes the first step in mucin-type O-glycosylation by transferring N-acetylgalactosamine to serine and threonine residues of proteins. Research using GALNT15 antibody has shown that it localizes to the Golgi apparatus, where it modifies a wide range of secreted and membrane proteins. This modification influences protein folding, stability, and interactions, highlighting its role in protein quality control.
Studies with GALNT15 antibody have revealed tissue-specific expression patterns, with high expression in reproductive tissues, brain, and gastrointestinal tract. This suggests specialized functions in mucosal barrier biology, fertility, and neuronal signaling. Isoform diversity further expands substrate specificity and biological functions of GALNT15.
Altered expression of GALNT15 has been implicated in cancer. Research using GALNT15 antibody has shown that abnormal glycosylation contributes to tumor progression by modifying adhesion molecules, receptors, and enzymes. Aberrant GALNT15 activity alters cell-cell communication and extracellular matrix interactions, promoting invasion and metastasis. These findings demonstrate its importance in tumor biology and potential as a biomarker.
In addition to cancer, variations in GALNT15 expression and function have been associated with infertility and neurological disease. Studies with GALNT15 antibody have suggested roles in sperm maturation and brain development. These findings expand its relevance beyond glycosylation to systemic physiology.
GALNT15 antibody is widely applied in western blotting, immunohistochemistry, and immunofluorescence. Western blotting quantifies isoforms and expression levels, immunohistochemistry identifies expression in tissue sections, and immunofluorescence demonstrates Golgi localization. These approaches make GALNT15 antibody essential for glycosylation research.
By supplying validated GALNT15 antibody reagents, NSJ Bioreagents supports studies into glycosylation, cancer, and reproductive biology. Detection of Polypeptide N-acetylgalactosaminyltransferase 15 provides researchers with insights into how glycan modification regulates protein function and disease mechanisms. -
UniProt
- Q8N3T1
抗原
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