TK2 抗体 (AA 34-265)
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Quick Overview for TK2 抗体 (AA 34-265) (ABIN7874071)
抗原
See all TK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 34-265
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原理
- Thymidine Kinase 2 Antibody / TK2
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids V34-P265) was used as the immunogen for the Thymidine Kinase 2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Thymidine Kinase 2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Thymidine Kinase 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- TK2 (Thymidine Kinase 2, Mitochondrial (TK2))
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别名
- Thymidine Kinase 2
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背景
- Thymidine kinase 2, mitochondrial is a protein that in humans is encoded by the TK2 gene. This gene encodes a deoxyribonucleoside kinase that specifically phosphorylates thymidine, deoxycytidine, and deoxyuridine. The encoded enzyme localizes to the mitochondria and is required for mitochondrial DNA synthesis. Mutations in this gene are associated with a myopathic form of mitochondrial DNA depletion syndrome. Alternate splicing results in multiple transcript variants encoding distinct isoforms, some of which lack transit peptide, so are not localized to mitochondria.
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UniProt
- O00142
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途径
- Mitotic G1-G1/S Phases
抗原
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