MSRA 抗体 (AA 34-215)
Our Local Distributor
北京 101111
Quick Overview for MSRA 抗体 (AA 34-215) (ABIN7874064)
抗原
See all MSRA 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 34-215
-
原理
- MSRA Antibody / Peptide methionine sulfoxide reductase A
-
纯化方法
- Immunogen affinity purified
-
免疫原
- E.coli-derived human MSRA recombinant protein (Position: Q34-N215) was used as the immunogen for the MSRA antibody.
-
亚型
- IgG
-
-
anti-Methionine Sulfoxide Reductase A (MSRA) (AA 27-235) antibody
MSRA 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Methionine Sulfoxide Reductase A (MSRA) (AA 1-100) antibodyMSRA 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3C11 unconjugated
anti-Methionine Sulfoxide Reductase A (MSRA) (AA 34-63), (N-Term) antibodyMSRA 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB18651 unconjugated
anti-Methionine Sulfoxide Reductase A (MSRA) (AA 1-235) antibodyMSRA 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Methionine Sulfoxide Reductase A (MSRA) (AA 1-235) antibodyMSRA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Methionine Sulfoxide Reductase A (MSRA) (C-Term) antibodyMSRA 适用: 人, 小鼠, 大鼠, 犬, Pig, 马, 兔, 豚鼠, 猴, Bat, 小鸡 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Methionine Sulfoxide Reductase A (MSRA) (AA 24-235) antibodyMSRA 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Methionine Sulfoxide Reductase A (MSRA) antibodyMSRA 适用: 人, 小鼠 WB, IHC, FACS, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Methionine Sulfoxide Reductase A (MSRA) (AA 27-235) antibodyMSRA 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C13 unconjugated
anti-Methionine Sulfoxide Reductase A (MSRA) (AA 1-100) antibodyMSRA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C11 unconjugated
-
-
应用备注
- Optimal dilution of the MSRA antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the MSRA antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- MSRA (Methionine Sulfoxide Reductase A (MSRA))
-
别名
- MSRA
-
背景
-
MSRA antibody detects Peptide methionine sulfoxide reductase A, encoded by the MSRA gene. Peptide methionine sulfoxide reductase A is an enzyme that reduces oxidized methionine residues in proteins, repairing oxidative damage and maintaining protein function. MSRA antibody provides researchers with a specific reagent for studying oxidative stress responses, protein repair, and aging.
Peptide methionine sulfoxide reductase A belongs to the methionine sulfoxide reductase family of antioxidant enzymes. Research using MSRA antibody has shown that it catalyzes the stereospecific reduction of methionine-S-sulfoxide back to methionine. This activity restores protein structure and function after oxidative damage, contributing to cellular protection against reactive oxygen species.
Studies with MSRA antibody have revealed that the enzyme is expressed in multiple tissues, including brain, liver, and heart. Its localization to cytoplasm and mitochondria allows it to safeguard proteins in compartments most vulnerable to oxidative stress. This dual localization emphasizes its importance in protecting cellular integrity.
Dysregulation of Peptide methionine sulfoxide reductase A has been linked to neurodegenerative disease, cardiovascular pathology, and aging. Research using MSRA antibody has shown that deficiency accelerates accumulation of damaged proteins, impairing neuronal survival and increasing vulnerability to oxidative stress. Conversely, overexpression of MSRA extends lifespan in model organisms and enhances resistance to oxidative injury. These findings suggest therapeutic potential in oxidative stress-related diseases.
MSRA antibody is widely used in western blotting, immunohistochemistry, and enzyme activity studies. Western blotting quantifies levels across tissues and conditions, immunohistochemistry demonstrates expression in brain and heart, and enzymatic assays confirm repair activity. These approaches make MSRA antibody indispensable in oxidative biology and aging research.
By supplying validated MSRA antibody reagents, NSJ Bioreagents supports studies into oxidative stress, protein repair, and disease. Detection of Peptide methionine sulfoxide reductase A provides researchers with insight into how antioxidant enzymes maintain protein quality and healthspan. -
UniProt
- Q9UJ68
抗原
-
