SIM2 抗体 (AA 337-609)
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Quick Overview for SIM2 抗体 (AA 337-609) (ABIN7874056)
抗原
See all SIM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 337-609
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原理
- SIM2 Antibody / Single-minded homolog 2 / BHLHE15
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived human recombinant protein (amino acids Y337-R609) was used as the immunogen for the SIM2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the SIM2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SIM2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SIM2 (Single-Minded Homolog 2 (SIM2))
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别名
- SIM2
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背景
- Single-minded homolog 2 is a protein that in humans is encoded by the SIM2 gene. This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
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UniProt
- Q14190
抗原
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