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MYCN 抗体 (AA 335-463)

The 小鼠 单克隆 anti-MYCN antibody is suitable to detect MYCN in samples from 人. It has been validated for ELISA 和 FACS.
产品编号 ABIN7874046
发货至: 中国
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Quick Overview for MYCN 抗体 (AA 335-463) (ABIN7874046)

抗原

See all MYCN 抗体
MYCN (N-Myc Proto-Oncogene Protein (MYCN))

适用

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宿主

  • 48
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小鼠

克隆类型

  • 48
  • 23
单克隆

标记

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This MYCN antibody is un-conjugated

应用范围

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ELISA, Flow Cytometry (FACS)

克隆位点

PCRP-MYCN-1A9
  • 抗原表位

    • 15
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    AA 335-463

    原理

    MYCN Antibody / n-Myc

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant human MYCN protein (within amino acids 335-463) was used as the immunogen for the MYCN antibody.

    亚型

    IgG1
  • 应用备注

    Optimal dilution of the MYCN antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the MYCN antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    MYCN (N-Myc Proto-Oncogene Protein (MYCN))

    别名

    MYCN

    背景

    The v-Myc oncogene, initially identified in the MC29 avian retrovirus, causes myelocytomas, carcinomas, sarcomas and lymphomas, and belongs to a family of oncogenes conserved throughout evolution. In humans, the family consists of five genes: c-Myc, N-Myc, R-Myc, L-Myc and B-Myc. Amplification of the N-Myc gene has been found in human neuroblastomas and cell lines. Its amplification correlates well with the stage of neuroblastoma disease. Immunological studies have shown that the human N-Myc gene encodes a nuclear phosphoprotein that exhibits relatively short (30 min) half life in vivo. The prototype member of the family, c-Myc p67, binds DNA in a sequence-specific manner subsequent to dimerization with a second basic region helix-loop-helix leucine zipper motif protein, designated Max.

    UniProt

    P04198
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