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TYR 抗体 (AA 332-474)

The 小鼠 单克隆 anti-TYR antibody is suitable to detect TYR in samples from 人. It has been validated for IF, FACS 和 IHC (p).
产品编号 ABIN7874028
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TYR 抗体 (AA 332-474) (ABIN7874028)

抗原

See all TYR 抗体
TYR (Tyrosinase (TYR))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This TYR antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

TYR-3829
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    AA 332-474

    原理

    Tyrosinase Antibody / TYR (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A portion of amino acids 332-474 was used as the immunogen for the Tyrosinase antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the Tyrosinase antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the Tyrosinase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    TYR (Tyrosinase (TYR))

    别名

    Tyrosinase

    背景

    Recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway, the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this MAb shows tyrosinase in melanotic as well as amelanotic variants. This MAb is a useful marker for melanocytes and melanomas.

    UniProt

    P14679
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