Mu Opioid Receptor 1 抗体 (AA 33-321)
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Quick Overview for Mu Opioid Receptor 1 抗体 (AA 33-321) (ABIN7873997)
抗原
See all Mu Opioid Receptor 1 (OPRM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 33-321
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原理
- MOR-1 Antibody / Mu-type Opioid Receptor / OPRM1
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids N33-H321) was used as the immunogen for the MOR-1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the MOR-1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the MOR-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Mu Opioid Receptor 1 (OPRM1) (Opioid Receptor, mu 1 (OPRM1))
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别名
- MOR-1
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背景
- This gene encodes one of at least three opioid receptors in humans, the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains.
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UniProt
- P35372
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途径
- cAMP Metabolic Process, Synaptic Membrane
抗原
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