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ANTXR1 抗体 (AA 33-301)

The 兔 多克隆 anti-ANTXR1 antibody (ABIN7873996) specifically detects ANTXR1 in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7873996
发货至: 中国
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Quick Overview for ANTXR1 抗体 (AA 33-301) (ABIN7873996)

抗原

See all ANTXR1 抗体
ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))

适用

  • 69
  • 29
  • 13
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 62
  • 4
  • 3

克隆类型

  • 65
  • 4
多克隆

标记

  • 30
  • 4
  • 4
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ANTXR1 antibody is un-conjugated

应用范围

  • 43
  • 30
  • 14
  • 13
  • 13
  • 12
  • 7
  • 5
  • 3
  • 3
  • 3
Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 8
    • 8
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 33-301

    原理

    TEM8 Antibody / Anthrax toxin receptor / ATR / ANTXR1

    纯化方法

    Antigen affinity purified

    免疫原

    Recombinant human protein (amino acids E33-D301) was used as the immunogen for the TEM8 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the TEM8 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the TEM8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))

    别名

    TEM8

    背景

    Anthrax toxin receptor 1 (ANTXR1 or also known as TEM8) is a protein that in humans is encoded by the ANTXR1 gene. This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.

    UniProt

    Q9H6X2
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