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SAP130 抗体 (AA 309-913)

The 兔 多克隆 anti-SAP130 antibody is suitable to detect SAP130 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IHC (p), IF 和 FACS.
产品编号 ABIN7873743
发货至: 中国
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Quick Overview for SAP130 抗体 (AA 309-913) (ABIN7873743)

抗原

See all SAP130 抗体
SAP130 (Sin3A-Associated Protein, 130kDa (SAP130))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 36
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多克隆

标记

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This SAP130 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 抗原表位

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    AA 309-913

    原理

    SAP130 Antibody / Sin3-associated polypeptide p130

    纯化方法

    Antigen affinity purified

    免疫原

    E. coli-derived recombinant human protein (amino acids H309-H913) was used as the immunogen for the SAP130 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the SAP130 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the SAP130 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    SAP130 (Sin3A-Associated Protein, 130kDa (SAP130))

    别名

    SAP130

    背景

    Histone deacetylase complex subunit SAP130 is an enzyme that in humans is encoded by the SAP130 gene. This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.

    UniProt

    Q9H0E3
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