Huntingtin 抗体 (AA 3079-3142)
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Quick Overview for Huntingtin 抗体 (AA 3079-3142) (ABIN7873734)
抗原
See all Huntingtin (HTT) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 3079-3142
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原理
- HTT Antibody / Huntingtin
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived human recombinant protein (amino acids R3079-C3142) was used as the immunogen for the HTT antibody.
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亚型
- IgG
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anti-Huntingtin (HTT) antibody
KD Validated HTT 适用: 人 WB, ICC, IF (p), FACS 宿主: 兔 Monoclonal 23GB6285 unconjugated Recombinant Antibody
anti-Huntingtin (HTT) antibodyHTT 适用: 人 IHC, WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Huntingtin (HTT) (AA 81-190) antibodyHTT 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3F1 unconjugated
anti-Huntingtin (HTT) (AA 81-190) antibodyHTT 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E10 unconjugated
anti-Huntingtin (HTT) (AA 85-200) antibodyHTT 适用: 人, 大鼠, 小鼠, 兔, 猴, 马, 犬, 绵羊, Pig, Hamster, 豚鼠, 山羊, 驴, Cow, 小鸡, Cat, Avian WB, IF, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-Huntingtin (HTT) (AA 81-190) antibodyHTT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H6 unconjugated
anti-Huntingtin (HTT) (AA 782-920) antibodyHTT 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Huntingtin (HTT) (AA 81-190) antibodyHTT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F9 unconjugated
anti-Huntingtin (HTT) (AA 81-191) antibodyHTT 适用: 人 IHC, WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3F1 unconjugated
anti-Huntingtin (HTT) antibodyHTT 适用: 人 IHC, ELISA 宿主: 兔 Monoclonal 6F2 unconjugated Recombinant Antibody
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应用备注
- Optimal dilution of the HTT antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the HTT antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Huntingtin (HTT)
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别名
- HTT
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背景
- The huntingtin gene, also called HTT or HD (Huntington disease) gene, is the IT15 (interesting transcript 15) gene which codes for a protein called the huntingtin protein. It is mapped to 4p16.3. The protein has no sequence homology with other proteins and is highly expressed in neurons and tests in humans and rodents. HTT upregulates the expression of Brain Derived Neurotrophic Factor (BDNF) at the transcription level, and this gene is required for normal development. The HTT protein is involved in vesicle trafficking as it interacts with HIP1, a clathrin-binding protein, to mediate endocytosis, the absorption of materials into a cell. HTT was also visualized as punctate staining likely to represent nerve endings. What's more, wildtype HTT may function in the nucleus in the assembly of nuclear matrix-bound protein complexes involved with transcriptional repression and RNA processing.
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UniProt
- P42858
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途径
- PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport
抗原
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