Dopamine d2 Receptor 抗体 (AA 307-336)
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Quick Overview for Dopamine d2 Receptor 抗体 (AA 307-336) (ABIN7873732)
抗原
See all Dopamine d2 Receptor (DRD2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 307-336
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原理
- DRD2 Antibody / Dopamine D2 Receptor
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 307-336 from the human protein were used as the immunogen for the DRD2 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the DRD2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the DRD2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))
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别名
- DRD2
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背景
- This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia, other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.
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UniProt
- P14416
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途径
- Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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