SMURF2 抗体 (AA 303-387)
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Quick Overview for SMURF2 抗体 (AA 303-387) (ABIN7873725)
抗原
See all SMURF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 303-387
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原理
- SMURF2 Antibody
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纯化方法
- Affinity purified
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免疫原
- A human recombinant protein (amino acids W303-Q387) was used as the immunogen for the SMURF2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the SMURF2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SMURF2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SMURF2 (SMAD Specific E3 Ubiquitin Protein Ligase 2 (SMURF2))
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别名
- SMURF2
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背景
- E3 ubiquitin-protein ligase SMURF2 is an enzyme that in humans is encoded by the SMURF2 gene. The SMURF2 gene is mapped to chromosome 17q22-q23 based on sequence similarity between the SMURF2 sequence and a genomic contig. SMURF2 is a HECT domain E3 ubiquitin ligase involved in degradation of SMADs, TGF-beta receptor (TGFBR), and other substrates. It also functions in regulation of neuronal and planar cell polarity, induction of senescence, and tumor suppression.
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UniProt
- Q9HAU4
抗原
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