OPA1 抗体 (AA 302-568)
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Quick Overview for OPA1 抗体 (AA 302-568) (ABIN7873722)
抗原
See all OPA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 302-568
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原理
- Zebrafish Opa1 Antibody / Dynamin-like GTPase Opa1
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived zebrafish Opa1 recombinant protein (amino acids D302-Q568) was used as the immunogen for the Zebrafish Opa1 antibody.
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亚型
- Ig Fraction
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应用备注
- Optimal dilution of the Zebrafish Opa1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish Opa1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))
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别名
- Opa1
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背景
- Dynamin-like 120 kDa protein, mitochondrial is a protein that in humans is encoded by the OPA1 gene. It is mapped to 3q29. This protein regulates mitochondrial fusion and cristae structure in the inner mitochondrial membrane (IMM) and contributes to ATP synthesis and apoptosis. This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
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UniProt
- Q5U3A7
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途径
- Tube Formation
抗原
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