PAX7 抗体 (AA 301-505)
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北京 101111
Quick Overview for PAX7 抗体 (AA 301-505) (ABIN7873712)
抗原
See all PAX7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 301-505
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原理
- PAX-7 Antibody
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纯化方法
- Protein G affinity chromatography
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免疫原
- Recombinant human PAX7 protein corresponding to amino acids 301-505 was used as the immunogen for this PAX-7 antibody.
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亚型
- IgG1, kappa
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应用备注
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Optimal dilution of the PAX-7 antibody should be determined by the researcher.
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris buffer with 1 mM EDTA, pH 9, for 10-20 min followed by cooling at RT for 20 min
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the PAX-7 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- PAX7 (Paired Box 7 (PAX7))
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别名
- PAX-7
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背景
- The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).
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UniProt
- P23759
抗原
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