RAPTOR 抗体 (AA 301-358)
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Quick Overview for RAPTOR 抗体 (AA 301-358) (ABIN7873706)
抗原
See all RAPTOR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-358
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原理
- Raptor Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids R301-R358) was used as the immunogen for the Raptor antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Raptor antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Raptor antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- RAPTOR
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别名
- Raptor
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背景
- Regulatory-associated protein of mTOR also known as raptor or KIAA1303 is an adapter protein that is encoded in humans by the RPTOR gene. This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene.
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UniProt
- Q8N122
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途径
- Warburg Effect
抗原
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