ENPP3 抗体 (AA 300-600)
Our Local Distributor
北京 101111
Quick Overview for ENPP3 抗体 (AA 300-600) (ABIN7873683)
抗原
See all ENPP3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 300-600
-
原理
- CD203c Antibody / ENPP3 / PD-Ibeta / PDNP3
-
纯化方法
- Protein A/G affinity
-
免疫原
- A portion of amino acids 300-600 from human ENPP3 protein was used as the immunogen for the CD203c antibody.
-
亚型
- IgG, kappa
-
-
-
-
应用备注
- Optimal dilution of the CD203c antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.2 mg/mL
-
缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the CD203c antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))
-
别名
- CD203c
-
背景
- Ecto-nucleotide pyrophosphatase/phosphodiesterase-I enzymes (E-NPP), a group of type II transmembrane proteins, cleave phosphodiester and phosphosulfate bonds in deoxynucleotides, NAD, and nucleotide sugars. There exist three closely related proteins in mammalian species: E-NPP1 (PC-1), E-NPP2 (PDNP2), and E-NPP-3, also known as CD203c, each expressed in different cells or at different locations in the same cells. Basophils, a type of major proinflammatory effector cells involved in diverse pathologic reactions, exhibit CD203c expression. For instance, CD203c expression increases in response to a variety of allergens, including cat dander, latex, and bee and wasp venom. However, these allergies are not the only condition associated with CD203c upregulation, CD203c upregulation may also serve as a tumor marker for colon carcinoma.
-
UniProt
- O14638
-
途径
- Regulation of Muscle Cell Differentiation, Negative Regulation of Transporter Activity
抗原
-