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Recombinant SOX11 抗体 (AA 300-400)

The 兔 单克隆 anti-SOX11 antibody is suitable to detect SOX11 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7873608
发货至: 中国
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Quick Overview for Recombinant SOX11 抗体 (AA 300-400) (ABIN7873608)

抗原

See all SOX11 抗体
SOX11 (SRY (Sex Determining Region Y)-Box 11 (SOX11))

抗体类型

Recombinant Antibody

适用

  • 70
  • 33
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宿主

  • 60
  • 10
  • 2

克隆类型

  • 40
  • 32
单克隆

标记

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This SOX11 antibody is un-conjugated

应用范围

  • 45
  • 26
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  • 8
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  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

SOX11-3235R
  • 抗原表位

    • 9
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    • 1
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    AA 300-400

    原理

    Recombinant SOX11 Antibody (azide and preservative free)

    纯化方法

    Protein A affinity chromatography

    免疫原

    A portion of amino acids 300-400 from the human protein was used as the immunogen for the recombinant SOX11 antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the recombinant SOX11 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the recombinant SOX11 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    SOX11 (SRY (Sex Determining Region Y)-Box 11 (SOX11))

    别名

    SOX11

    背景

    Recognizes a protein of ~47 kDa, identified as SOX11. This MAb is highly specific and does not cross-react with other members of the SOX-family. Mantle cell lymphoma (MCL) accounts for 5 % to 10 % of mature B-cell neoplasms and is an aggressive disease genetically characterized by overexpression of Cyclin D1. Cyclin D1 overexpression is the hallmark of MCL. However, approximately 5 %-10 % of MCLs lack Cyclin D1 expression and may be misdiagnosed. Almost all Cyclin D1-positive as well as Cyclin D1-negative MCL, show overexpression of SOX-11. The detection of this transcription factor is a useful biomarker for identifying true cyclin D1-negative MCL.

    UniProt

    P35716

    途径

    Tube Formation
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