HTRA2 抗体 (AA 30-458)
Our Local Distributor
北京 101111
Quick Overview for HTRA2 抗体 (AA 30-458) (ABIN7873586)
抗原
See all HTRA2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 30-458
-
原理
- OMI Antibody / HTRA2
-
纯化方法
- Antigen affinity chromatography
-
免疫原
- An E.coli-derived human recombinant protein (amino acids R30-E458) was used as the immunogen for the OMI antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the OMI antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the OMI Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
-
别名
- OMI
-
背景
- Serine protease HTRA2, mitochondrial, also called Omi stress-regulated endoprotease (OMI), is an enzyme that in humans is encoded by the HTRA2 gene. This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
-
UniProt
- O43464
-
途径
- Positive Regulation of Endopeptidase Activity
抗原
-