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BCR 抗体 (AA 3-264)

The 兔 多克隆 anti-BCR antibody (ABIN7873528) specifically detects BCR in WB, ELISA 和 FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7873528
发货至: 中国
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Quick Overview for BCR 抗体 (AA 3-264) (ABIN7873528)

抗原

See all BCR 抗体
BCR (Breakpoint Cluster Region (BCR))

适用

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  • 57
  • 29
  • 5
  • 2
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  • 1
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  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 107
  • 6
  • 4

克隆类型

  • 98
  • 19
多克隆

标记

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  • 5
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This BCR antibody is un-conjugated

应用范围

  • 85
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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

    • 30
    • 16
    • 8
    • 4
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    • 3
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    • 2
    • 2
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 3-264

    原理

    Breakpoint cluster region protein Antibody / BCR

    纯化方法

    Antigen affinity purified

    免疫原

    Recombinant human protein (amino acids D3-N264) was used as the immunogen for the Breakpoint cluster region protein antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Breakpoint cluster region protein antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Breakpoint cluster region protein antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    BCR (Breakpoint Cluster Region (BCR))

    别名

    Breakpoint cluster region protein

    背景

    The breakpoint cluster region protein (BCR) is a protein that in humans is encoded by the BCR gene. A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.

    UniProt

    P11274

    途径

    Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling
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