TNNI2 抗体 (AA 3-182)
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Quick Overview for TNNI2 抗体 (AA 3-182) (ABIN7873521)
抗原
See all TNNI2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 3-182
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原理
- TNNI2 Antibody
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纯化方法
- Affinity purified
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免疫原
- A human recombinant protein (amino acids D3-S182) was used as the immunogen for the TNNI2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the TNNI2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the TNNI2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- TNNI2 (Fast Skeletal Troponin I (TNNI2))
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别名
- TNNI2
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背景
- Troponin I, fast skeletal muscle is a protein that in humans is encoded by the TNNI2 gene. It is mapped to 11p15.5. This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene.
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UniProt
- P48788
抗原
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