DBF4 抗体 (AA 295-665)
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Quick Overview for DBF4 抗体 (AA 295-665) (ABIN7873463)
抗原
See all DBF4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 295-665
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原理
- DBF4 Antibody
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids Y295-S665) was used as the immunogen for the DBF4 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the DBF4 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the DBF4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- DBF4 (DBF4 Homolog (DBF4))
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别名
- DBF4
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背景
- Using both gain- and loss-of-function experiments, it was found that Xenopus Dbf4 inhibited canonical Wnt signaling. Depletion of endogenous Dbf4 did not disturb gastrulation movements or early organizer genes, but resulted in embryos with morphologically defective heart and eyes and suppressed cardiac markers. The function of Dbf4 in heart development appeared to be independent of its role in the cell cycle. Dbf4 interacted physically and functionally with Frodo, a context-dependent regulator of Wnt signaling.
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UniProt
- Q9UBU7
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途径
- Mitotic G1-G1/S Phases, DNA Replication
抗原
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