MMP13 抗体 (AA 295-324)
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Quick Overview for MMP13 抗体 (AA 295-324) (ABIN7873462)
抗原
See all MMP13 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 295-324
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原理
- Collagenase 3 Antibody / MMP13
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纯化方法
- Purified
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免疫原
- A portion of amino acids 295-324 from the human protein was used as the immunogen for the Collagenase 3 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Collagenase 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Collagenase 3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))
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别名
- Collagenase 3
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背景
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
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UniProt
- P45452
抗原
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