JHDM1D 抗体 (AA 290-316)
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Quick Overview for JHDM1D 抗体 (AA 290-316) (ABIN7873439)
抗原
See all JHDM1D 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 290-316
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原理
- JHDM1D Antibody / KDM7A
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 290-316 from the human protein was used as the immunogen for the JHDM1D antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the JHDM1D antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the JHDM1D antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- JHDM1D (Jumonji C Domain-Containing Histone Demethylase 1 Homolog D (JHDM1D))
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别名
- JHDM1D
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背景
- JHDM1D histone demethylase that specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3, thereby playing a central role in histone code. This specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. This demethylates H3K9me2 in absence of H3K4me3.
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UniProt
- Q6ZMT4
抗原
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