HIF3A 抗体 (AA 29-480)
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Quick Overview for HIF3A 抗体 (AA 29-480) (ABIN7873426)
抗原
See all HIF3A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 29-480
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原理
- HIF3A Antibody / Hypoxia-inducible factor 3 alpha
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids Q29-Q480) was used as the immunogen for the HIF3A antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the HIF3A antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the HIF3A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))
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别名
- HIF3A
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背景
- Hypoxia-inducible factor 3 alpha, also called MOP7, is a protein that in humans is encoded by the HIF3A gene. HIF3A is mapped to 19q13.32. This gene involved in adaptive response to hypoxia. HIF3A suppresses hypoxia-inducible expression of HIF1A and EPAS1. It binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters. The complex HIF3A-ARNT activates the transcription of reporter genes driven by HRE. This gene functions as an inhibitor of angiogenesis in the cornea.
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UniProt
- Q9Y2N7
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途径
- Warburg Effect
抗原
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