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GSTA4 抗体 (AA 29-222)

This 兔 多克隆 antibody specifically detects GSTA4 in WB, ELISA, FACS 和 IHC (p). It exhibits reactivity toward 人 和 猴.
产品编号 ABIN7873400
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GSTA4 抗体 (AA 29-222) (ABIN7873400)

抗原

See all GSTA4 抗体
GSTA4 (Glutathione S-Transferase alpha 4 (GSTA4))

适用

  • 50
  • 11
  • 9
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 猴

宿主

  • 54
  • 5
  • 1

克隆类型

  • 56
  • 4
多克隆

标记

  • 36
  • 9
  • 8
  • 2
  • 2
  • 2
  • 1
This GSTA4 antibody is un-conjugated

应用范围

  • 47
  • 29
  • 19
  • 15
  • 10
  • 9
  • 8
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 18
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 29-222

    原理

    GSTA4 Antibody

    纯化方法

    Affinity purified

    免疫原

    A human recombinant partial protein (amino acids E29-P222) was used as the immunogen for the GSTA4 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the GSTA4 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the GSTA4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    GSTA4 (Glutathione S-Transferase alpha 4 (GSTA4))

    别名

    GSTA4

    背景

    Glutathione S-transferase A4, also known as GSTA4, is an enzyme which in humans is encoded by the GSTA4 gene. Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver (hepatocytes) and kidney (proximal tubules). In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity, thereby protecting the cells from reactive oxygen species and the products of peroxidation.

    UniProt

    O15217
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