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Recombinant RBP4 抗体 (AA 29-148)

The 兔 单克隆 anti-RBP4 antibody (Clone RBP4-7045R) (ABIN7873345) specifically detects RBP4 in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7873345
发货至: 中国
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Quick Overview for Recombinant RBP4 抗体 (AA 29-148) (ABIN7873345)

抗原

See all RBP4 抗体
RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

抗体类型

Recombinant Antibody

适用

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宿主

  • 144
  • 93
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克隆类型

  • 137
  • 113
单克隆

标记

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This RBP4 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RBP4-7045R
  • 抗原表位

    • 61
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    AA 29-148

    原理

    Recombinant Retinol Binding Protein 4 Antibody / RBP4

    纯化方法

    Protein A/G affinity

    免疫原

    A portion of amino acids 29-148 was used as the immunogen for the recombinant Retinol Binding Protein 4 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the recombinant Retinol Binding Protein 4 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Aliquot the recombinant Retinol Binding Protein 4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

    别名

    Retinol Binding Protein 4

    背景

    Retinol (Vitamin A) is transported in the blood bound to its carrier protein, retinol-binding protein (RBP), also designated plasma retinol-binding protein (PRBP) or RBP4. A member of the lipocalin family, RBP conveys retinol from stores in the liver to peripheral tissues. In plasma, RBP binds transthyretin (TTR, formerly called prealbumin) to prevent glomerular filtration of low molecular weight RBP in the kidneys. The stability of this complex holds diagnostic importance because the molar ratio of RBP:TTR provides an indirect way to indicate marginal Vitamin A deficiency. Vitamin A deficiency blocks the secretion of RBP, resulting in defective delivery and supply to epidermal cells. Originally identified solely as a transporter protein, recent studies correlating increased levels of RBP expression in adipose tissue with Insulin resistance have generated research into the possible roles the protein may play in the pathogenesis of type 2 diabetes and obesity.

    UniProt

    P02753

    途径

    Regulatory RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
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