GPR81 抗体 (AA 287-316)
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北京 101111
Quick Overview for GPR81 抗体 (AA 287-316) (ABIN7873323)
抗原
See all GPR81 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 287-316
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原理
- HCAR1 Antibody / Hydroxycarboxylic acid receptor 1 / GPR81
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纯化方法
- Antigen affinity
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免疫原
- A portion of amino acids 287-316 from the human protein was used as the immunogen for the HCAR1 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the HCAR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the HCAR1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- GPR81 (G Protein-Coupled Receptor 81 (GPR81))
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别名
- HCAR1
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背景
- HCAR1 is a G-protein coupled receptor that is primarily found in various tissues throughout the body, including the liver, adipose tissue, and skeletal muscle. When activated by its ligand, which in this case is a specific type of hydroxycarboxylic acid, HCAR1 plays a key role in regulating glucose and lipid metabolism. One of the most intriguing aspects of HCAR1 is its ability to promote the use of fats as an energy source, a process known as fatty acid oxidation. By activating HCAR1, the body is able to break down fatty acids more efficiently, leading to improved metabolic health and potentially aiding in weight management. Additionally, HCAR1 has been shown to have anti-inflammatory effects, which can help combat chronic inflammation associated with metabolic disorders such as obesity and diabetes. By modulating the body's immune response, HCAR1 can help reduce inflammation and improve overall health.
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UniProt
- Q9BXC0
抗原
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