RORC 抗体 (AA 286-511)
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Quick Overview for RORC 抗体 (AA 286-511) (ABIN7873318)
抗原
See all RORC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 286-511
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原理
- ROR gamma Antibody / RORC
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids Q286-E511) was used as the immunogen for the ROR gamma antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the ROR gamma antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the ROR gamma antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- RORC (RAR-Related Orphan Receptor C (RORC))
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别名
- ROR gamma
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背景
- RAR-related orphan receptor gamma (RORg) is a protein that in humans is encoded by the RORC (RAR-related orphan receptor C) gene. The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.
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UniProt
- P51449
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途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
抗原
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