F11R 抗体 (AA 28-294)
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Quick Overview for F11R 抗体 (AA 28-294) (ABIN7873249)
抗原
See all F11R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 28-294
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原理
- Junctional adhesion molecule A Antibody / JAM-A / F11R
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids S28-T294) was used as the immunogen for the Junctional adhesion molecule A antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Junctional adhesion molecule A antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Junctional adhesion molecule A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- F11R (F11 Receptor (F11R))
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别名
- Junctional adhesion molecule A
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背景
- Junctional adhesion molecule A is a protein that in humans is encoded by the F11R gene. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
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UniProt
- Q9Y624
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途径
- Cell-Cell Junction Organization
抗原
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