WFS1 抗体 (AA 272-876)
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Quick Overview for WFS1 抗体 (AA 272-876) (ABIN7873171)
抗原
See all WFS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 272-876
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原理
- WFS1 Antibody / Wolframin
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids D272-K876) was used as the immunogen for the WFS1 antibody.
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亚型
- IgG
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anti-Wolfram Syndrome 1 (WFS1) (AA 61-313) antibody
WFS1 适用: 人, 猴 WB, IHC, ELISA, ICC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Wolfram Syndrome 1 (WFS1) (AA 1-285) antibodyWFS1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Wolfram Syndrome 1 (WFS1) (Internal Region) antibodyWFS1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Wolfram Syndrome 1 (WFS1) (AA 791-890) antibodyWFS1 适用: 人 WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the WFS1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the WFS1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- WFS1 (Wolfram Syndrome 1 (WFS1))
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别名
- WFS1
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背景
- Wolframin is a protein that in humans is encoded by the WFS1 gene. This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38. Alternatively spliced transcript variants have been found for this gene.
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UniProt
- O76024
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途径
- Sensory Perception of Sound, Carbohydrate Homeostasis, ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome
抗原
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