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CD43 抗体 (AA 272-400)

The 小鼠 单克隆 anti-CD43 antibody (Clone 4I3) (ABIN7873162) specifically detects CD43 in FACS, WB 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7873162
发货至: 中国
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Quick Overview for CD43 抗体 (AA 272-400) (ABIN7873162)

抗原

See all CD43 (SPN) 抗体
CD43 (SPN) (Sialophorin (SPN))

适用

  • 180
  • 17
  • 16
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 108
  • 92
  • 7
  • 1
小鼠

克隆类型

  • 135
  • 69
  • 4
单克隆

标记

  • 107
  • 17
  • 17
  • 15
  • 10
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CD43 antibody is un-conjugated

应用范围

  • 127
  • 113
  • 92
  • 65
  • 44
  • 30
  • 28
  • 24
  • 7
  • 6
  • 6
  • 4
  • 3
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

4I3
  • 抗原表位

    • 14
    • 10
    • 9
    • 8
    • 7
    • 7
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 272-400

    原理

    CD43 Antibody

    纯化方法

    Affinity purified

    免疫原

    A human recombinant protein (amino acids A272-P400) was used as the immunogen for the CD43 antibody.

    亚型

    IgG2b
  • 应用备注

    Optimal dilution of the CD43 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the CD43 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    CD43 (SPN) (Sialophorin (SPN))

    别名

    CD43

    背景

    CD43, also known as leukosialin or sialophorin, is a transmembrane cell surface protein that in humans is encoded by the SPN gene. It is mapped to 16p11.2. It is a major sialoglycoprotein on the surface of human T lymphocytes, monocytes, granulocytes, and some B lymphocytes, which is important for immune function and may be part of a physiologic ligand-receptor complex involved in T-cell activation. Expression of CD43 is deficient and/or defective in the X-chromosome-linked immunodeficiency disorder Wiscott-Aldrich syndrome, suggesting that CD43 have a role in T-cell activation. T-cell activation requires the removal of CD43 from the immunologic synapse to allow efficient engagement of the TCR with molecules on the APC.

    UniProt

    P16150

    途径

    Regulation of Leukocyte Mediated Immunity
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