CD43 抗体 (AA 272-400)
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Quick Overview for CD43 抗体 (AA 272-400) (ABIN7873162)
抗原
See all CD43 (SPN) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 272-400
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原理
- CD43 Antibody
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纯化方法
- Affinity purified
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免疫原
- A human recombinant protein (amino acids A272-P400) was used as the immunogen for the CD43 antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the CD43 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the CD43 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- CD43 (SPN) (Sialophorin (SPN))
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别名
- CD43
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背景
- CD43, also known as leukosialin or sialophorin, is a transmembrane cell surface protein that in humans is encoded by the SPN gene. It is mapped to 16p11.2. It is a major sialoglycoprotein on the surface of human T lymphocytes, monocytes, granulocytes, and some B lymphocytes, which is important for immune function and may be part of a physiologic ligand-receptor complex involved in T-cell activation. Expression of CD43 is deficient and/or defective in the X-chromosome-linked immunodeficiency disorder Wiscott-Aldrich syndrome, suggesting that CD43 have a role in T-cell activation. T-cell activation requires the removal of CD43 from the immunologic synapse to allow efficient engagement of the TCR with molecules on the APC.
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UniProt
- P16150
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途径
- Regulation of Leukocyte Mediated Immunity
抗原
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