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FBXW8 抗体 (AA 270-299)

The 兔 多克隆 anti-FBXW8 antibody is suitable to detect FBXW8 in samples from 人 和 小鼠. It has been validated for WB, FACS 和 IHC (p).
产品编号 ABIN7873149
发货至: 中国
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Quick Overview for FBXW8 抗体 (AA 270-299) (ABIN7873149)

抗原

See all FBXW8 抗体
FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))

适用

  • 18
  • 18
  • 9
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 32
  • 1

克隆类型

  • 33
多克隆

标记

  • 14
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FBXW8 antibody is un-conjugated

应用范围

  • 32
  • 14
  • 13
  • 13
  • 8
  • 8
  • 5
  • 3
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 7
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 270-299

    原理

    FBXW8 Antibody

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 270-299 from the human protein was used as the immunogen for the FBXW8 antibody.

    亚型

    Ig Fraction
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the FBXW8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the FBXW8 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))

    别名

    FBXW8

    背景

    This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

    UniProt

    Q8N3Y1
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