SSX2IP 抗体 (AA 27-614)
Our Local Distributor
北京 101111
Quick Overview for SSX2IP 抗体 (AA 27-614) (ABIN7873138)
抗原
See all SSX2IP 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 27-614
-
原理
- SSX2IP Antibody / SSX2 interacting protein
-
纯化方法
- Immunogen affinity purified
-
免疫原
- E.coli-derived human SSX2IP recombinant protein (Position: K27-P614) was used as the immunogen for the SSX2IP antibody.
-
亚型
- IgG
-
-
anti-Synovial Sarcoma, X Breakpoint 2 Interacting Protein (SSX2IP) (AA 485-614) antibody
SSX2IP 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Synovial Sarcoma, X Breakpoint 2 Interacting Protein (SSX2IP) (AA 362-411) antibodySSX2IP 适用: 人, 犬, Cow, 豚鼠, 马, 兔, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Synovial Sarcoma, X Breakpoint 2 Interacting Protein (SSX2IP) antibodyKD Validated SSX2IP 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3560 unconjugated Recombinant Antibody
anti-Synovial Sarcoma, X Breakpoint 2 Interacting Protein (SSX2IP) (AA 1-614) antibodySSX2IP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Synovial Sarcoma, X Breakpoint 2 Interacting Protein (SSX2IP) (AA 1-614) antibodySSX2IP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Synovial Sarcoma, X Breakpoint 2 Interacting Protein (SSX2IP) (C-Term) antibodySSX2IP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal dilution of the SSX2IP antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the SSX2IP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- SSX2IP (Synovial Sarcoma, X Breakpoint 2 Interacting Protein (SSX2IP))
-
别名
- SSX2IP
-
背景
-
SSX2IP antibody detects SSX2 interacting protein, encoded by the SSX2IP gene. SSX2 interacting protein is a centrosomal and basal body protein that regulates spindle assembly, ciliogenesis, and cell division. SSX2IP antibody provides researchers with a specific reagent for studying centrosome biology, ciliary function, and cancer progression.
SSX2 interacting protein was originally identified as an interaction partner of the cancer testis antigen SSX2. Research using SSX2IP antibody has shown that it localizes to centrosomes and spindle poles during mitosis, where it stabilizes microtubule anchoring. It is also recruited to basal bodies, where it contributes to ciliogenesis and cilia maintenance. These dual localizations highlight its importance in both cell division and ciliary function.
Studies with SSX2IP antibody have demonstrated that depletion of SSX2IP causes spindle defects, impaired chromosome segregation, and abnormal ciliogenesis. In developmental contexts, SSX2IP is required for normal ciliary signaling and embryogenesis. Its role in centrosome anchoring underscores its fundamental role in cell biology.
Dysregulation of SSX2 interacting protein has been associated with cancer and ciliopathies. Research using SSX2IP antibody has shown that overexpression occurs in acute myeloid leukemia and gastrointestinal cancers, where it promotes proliferation and survival. Deficiency in SSX2IP has been linked to ciliary defects and developmental abnormalities, emphasizing its importance in health and disease.
SSX2IP antibody is widely used in immunofluorescence, immunohistochemistry, and western blotting. Immunofluorescence highlights centrosomal and basal body localization, immunohistochemistry demonstrates tumor expression, and western blotting quantifies levels across development and disease models. These applications make SSX2IP antibody indispensable in centrosome and cancer research.
By providing validated SSX2IP antibody reagents, NSJ Bioreagents supports studies into spindle regulation, ciliary biology, and oncogenesis. Detection of SSX2 interacting protein provides researchers with insight into how centrosomal proteins contribute to division and disease. -
UniProt
- Q9Y2D8
抗原
-
