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IL-11 抗体 (AA 27-61)

The 兔 多克隆 anti-IL-11 antibody is suitable to detect IL-11 in samples from 人. It has been validated for WB.
产品编号 ABIN7873137
发货至: 中国
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Quick Overview for IL-11 抗体 (AA 27-61) (ABIN7873137)

抗原

See all IL-11 (IL11) 抗体
IL-11 (IL11) (Interleukin 11 (IL11))

适用

  • 53
  • 27
  • 25

宿主

  • 45
  • 21
  • 6
  • 1

克隆类型

  • 45
  • 28
多克隆

标记

  • 40
  • 7
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IL-11 antibody is un-conjugated

应用范围

  • 50
  • 37
  • 17
  • 15
  • 13
  • 13
  • 7
  • 6
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 27-61

    原理

    IL-11 Antibody (N-Terminal Region)

    纯化方法

    Antigen affinity

    免疫原

    A portion of amino acids 27-61 from human IL-11 was used as the immunogen for the IL-11 antibody.

    亚型

    Ig Fraction
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the IL-11 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the IL-11 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    IL-11 (IL11) (Interleukin 11 (IL11))

    别名

    IL-11

    背景

    Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed: 2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:< a href=http://www.uniprot.org/citations/12919066 target=_blank>12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. [UniProt]

    UniProt

    P20809

    途径

    JAK/STAT Signaling, Negative Regulation of Hormone Secretion
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