Azurocidin 抗体 (AA 27-245)
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Quick Overview for Azurocidin 抗体 (AA 27-245) (ABIN7873103)
抗原
See all Azurocidin (AZU1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 27-245
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原理
- Azurocidin Antibody / AZU1 / CAP37
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids I27-N245) was used as the immunogen for the Azurocidin antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Azurocidin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Azurocidin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Azurocidin (AZU1) (Azurocidin 1 (AZU1))
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别名
- Azurocidin
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背景
- Azurocidin also known as cationic antimicrobial protein CAP37 or heparin-binding protein (HBP) is a protein that in humans is encoded by the AZU1 gene. Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.
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UniProt
- P20160
抗原
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