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PDCD1LG2 抗体 (AA 27-220)

The 小鼠 单克隆 anti-PDCD1LG2 antibody is suitable to detect PDCD1LG2 in samples from 人. It has been validated for WB, FACS, ELISA 和 IF.
产品编号 ABIN7873098
发货至: 中国
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Quick Overview for PDCD1LG2 抗体 (AA 27-220) (ABIN7873098)

抗原

See all PDCD1LG2 抗体
PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This PDCD1LG2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunofluorescence (IF)

质量等级

Carrier-free

克隆位点

PDL2-2676
  • 抗原表位

    • 28
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    AA 27-220

    原理

    PD-L2 Antibody (azide and preservative free)

    纯化方法

    Protein G affinity chromatography

    免疫原

    A recombinant fragment of human PD-L2 protein within amino acids 27-220 was used as the immunogen for the PD-L2 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the PD-L2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the PD-L2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

    别名

    PD-L2

    背景

    Recognizes a protein identified as PD-L2 (same as PDCD1LG2). Engagement of CD28 by B7-1 (CD80) or B7-2 (CD86) in the presence of antigen promotes T cell proliferation, cytokine production, differentiation of effector T cells and the induction of Bcl-x, a promoter of T cell survival. Conversely, engagement of CTLA4 by B7-1 or B7-2 may inhibit proliferation and IL-2 production. PD-L2 does not bind CD28, cytotoxic T lymphocyte A4 or ICOS (inducible co-stimulator). The constitutive expression of PD-L1 and PD-L2 on parenchymal cells of heart, lung and kidney suggests that the Pdcd-1-Pdcd-L system could provide unique negative signaling to help prevent autoimmune disease.

    UniProt

    Q9BQ51
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