PDCD1LG2 抗体 (AA 27-220)
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Quick Overview for PDCD1LG2 抗体 (AA 27-220) (ABIN7873096)
抗原
See all PDCD1LG2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 27-220
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原理
- PDL2 Antibody / Programmed death ligand 2 / CD273 (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- A recombinant fragment of human PD-L2 protein within amino acids 27-220 was used as the immunogen for the PDL2 antibody.
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亚型
- IgG1, kappa
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anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 21-118) antibody
PDCD1LG2 适用: 人 WB, FACS, IHC, ELISA, IP, IF 宿主: 小鼠 Monoclonal 7F11D11 unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 27-220) antibodyPDCD1LG2 适用: 人 WB, FACS, ELISA, IF 宿主: 小鼠 Monoclonal PDL2-2676 unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 33-236) antibodyPDCD1LG2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 36-219) antibodyPDCD1LG2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) antibody (PE)PDCD1LG2 适用: 人 FACS 宿主: 小鼠 Monoclonal 24F-10C12 PE
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) antibodyPDCD1LG2 适用: 人 FACS, IHC 宿主: 小鼠 Monoclonal 24F-10C12 unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 21-268) antibodyPDCD1LG2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 22-111) antibodyPDCD1LG2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7D5 unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-220) antibodyPDCD1LG2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Monoclonal BLR277L unconjugated Recombinant Antibody
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 46-75), (N-Term) antibodyPDCD1LG2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB31095 unconjugated
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应用备注
- Optimal dilution of the PDL2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the PDL2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
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别名
- PDL2
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背景
- Recognizes a protein of about 31 kDa, which is identified as PD-L2 (same as PDCD1LG2). Engagement of CD28 by B7-1 (CD80) or B7-2 (CD86) in the presence of antigen promotes T cell proliferation, cytokine production, differentiation of effector T cells and the induction of Bcl-x, a promoter of T cell survival. Conversely, engagement of CTLA4 by B7-1 or B7-2 may inhibit proliferation and IL-2 production. PD-L2 does not bind CD28, cytotoxic T lymphocyte A4 or ICOS (inducible co-stimulator). The constitutive expression of PD-L1 and PD-L2 on parenchymal cells of heart, lung and kidney suggests that the Pdcd-1-Pdcd-L system could provide unique negative signaling to help prevent autoimmune disease.
抗原
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