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TGIF1 抗体 (AA 26-401)

This 兔 多克隆 antibody specifically detects TGIF1 in WB, ELISA 和 FACS. It exhibits reactivity toward 人.
产品编号 ABIN7873001
发货至: 中国
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Quick Overview for TGIF1 抗体 (AA 26-401) (ABIN7873001)

抗原

See all TGIF1 抗体
TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

适用

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宿主

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克隆类型

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多克隆

标记

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This TGIF1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

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    AA 26-401

    原理

    TGIF1 Antibody / 5-TG-3-interacting factor 1 / TGIF

    纯化方法

    Antigen affinity purified

    免疫原

    E. coli-derived recombinant human protein (amino acids D26-A401) was used as the immunogen for the TGIF1 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the TGIF1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the TGIF1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

    别名

    TGIF1

    背景

    Homeobox protein TGIF1 is a protein that in humans is encoded by the TGIF1 gene. The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and multiple splice variants encoding distinct isoforms are described.

    UniProt

    Q15583

    途径

    Retinoic Acid Receptor Signaling Pathway, Chromatin Binding, Tube Formation
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