GATA6 抗体 (AA 26-296)
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Quick Overview for GATA6 抗体 (AA 26-296) (ABIN7872994)
抗原
See all GATA6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 26-296
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原理
- Zebrafish Gata6 Antibody / GATA-binding factor 6
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纯化方法
- Antigen affinity chromatography
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免疫原
- E. coli-derived zebrafish Gata6 recombinant protein (amino acids E26-E296) was used as the immunogen for the Zebrafish Gata6 antibody.
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亚型
- Ig Fraction
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应用备注
- Optimal dilution of the Zebrafish Gata6 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish Gata6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- GATA6 (GATA Binding Protein 6 (GATA6))
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别名
- Gata6
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背景
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GATA-binding protein 6 (Gata6) is a zinc finger transcription factor belonging to the GATA family, which regulates gene expression during embryonic development and cell lineage specification. In zebrafish (Danio rerio), Gata6 plays a key role in the development of the endoderm, heart, and gut, as well as in organ morphogenesis and tissue differentiation.
During early zebrafish embryogenesis, Gata6 is expressed in the endodermal and mesodermal layers, where it works in concert with Gata4 and Gata5 to specify endodermal fate and initiate the morphogenesis of organs such as the liver, pancreas, and intestine. It also contributes to cardiac progenitor specification and the formation of the heart tube, making it essential for proper cardiovascular development.
Due to its high conservation and central role in organogenesis, zebrafish Gata6 is widely used as a model to study developmental gene regulation, cardiogenesis, and congenital diseases affecting the heart and gastrointestinal tract. It is also a valuable marker for analyzing endodermal derivatives and early tissue patterning in vertebrate embryos.
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UniProt
- Q6NW63
抗原
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