PIEZO2 抗体 (AA 2575-2604)
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Quick Overview for PIEZO2 抗体 (AA 2575-2604) (ABIN7872967)
抗原
See all PIEZO2 (FAM38B) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2575-2604
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原理
- PIEZO2 Antibody / FAM38B
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纯化方法
- Antigen affinity
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免疫原
- A portion of amino acids 2575-2604 from the human protein was used as the immunogen for the PIEZO2 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the PIEZO2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the PIEZO2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PIEZO2 (FAM38B) (Family with Sequence Similarity 38, Member B (FAM38B))
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别名
- PIEZO2
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背景
- PIEZO2 (Piezo-type mechanosensitive ion channel component 2), also called Protein FAM38B, is a transmembrane protein that spans the cell membrane and acts as a sensor for mechanical stimuli. When external forces, such as touch or pressure, are applied to the cell membrane, PIEZO2 responds by opening up and allowing ions to flow into the cell. This influx of ions triggers a signal that is transmitted to the brain, allowing us to perceive and respond to the touch sensation. It also plays a critical role in a variety of other sensory functions, including proprioception (the ability to sense the position of our body in space) and hearing. Recent studies have uncovered even more functions of PIEZO2 beyond sensory perception. It has been found to be involved in regulating lung development, bone formation, and even cell migration.
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UniProt
- Q9H5I5
抗原
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