IL1RL2 抗体 (AA 257-286)
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Quick Overview for IL1RL2 抗体 (AA 257-286) (ABIN7872954)
抗原
See all IL1RL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 257-286
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原理
- IL1RL2 Antibody / Interleukin-1 receptor-like 2
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纯化方法
- Antigen affinity
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免疫原
- A portion of amino acids 257-286 from the human protein was used as the immunogen for this IL1RL2 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the IL1RL2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4oC for up to one month. For long term, aliquot the IL1RL2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))
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别名
- IL1RL2
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背景
- IL1RL2, also known as interleukin-1 receptor-like 2, is a protein that belongs to the IL-1 receptor family. It is primarily expressed on the surface of immune cells, where it binds to specific ligands and triggers a cascade of signaling pathways that ultimately lead to the activation of immune responses. Studies have shown that IL1RL2 plays a critical role in the pathogenesis of various inflammatory diseases, such as asthma, rheumatoid arthritis, and inflammatory bowel disease. One of the key functions of IL1RL2 is its ability to regulate the production of pro-inflammatory cytokines, such as IL-6 and IL-8, which are responsible for promoting inflammation in the body. By modulating the activity of these cytokines, IL1RL2 helps to maintain the balance between pro-inflammatory and anti-inflammatory responses, thereby preventing excessive inflammation and tissue damage. Furthermore, IL1RL2 has also been shown to play a role in the activation of T cells and other immune cells, which are essential for mounting an effective immune response against pathogens.
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UniProt
- Q9HB29
抗原
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