SH3BP2 抗体 (AA 256-561)
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Quick Overview for SH3BP2 抗体 (AA 256-561) (ABIN7872952)
抗原
See all SH3BP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 256-561
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原理
- 3BP2 Antibody / SH3 domain-binding protein 2 / SH3BP2
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids R256-R561) was used as the immunogen for the 3BP2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the 3BP2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the 3BP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))
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别名
- 3BP2
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背景
- SH3BP2 (SH3 domain-binding protein 2) is a protein that comes from a gene located on Chromosome 4. The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.
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UniProt
- P78314
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途径
- TCR Signaling
抗原
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