Rhotekin 抗体 (AA 255-554)
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Quick Overview for Rhotekin 抗体 (AA 255-554) (ABIN7872939)
抗原
See all Rhotekin (RTKN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 255-554
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原理
- Rhotekin Antibody / RTKN
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids R255-Q554) was used as the immunogen for the Rhotekin antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Rhotekin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Rhotekin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Rhotekin (RTKN)
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别名
- Rhotekin
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背景
- Rhotekin is a protein that in humans is encoded by the RTKN gene. This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
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UniProt
- Q9BST9
抗原
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