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Cyclin T1 抗体 (AA 253-281)

The 兔 多克隆 anti-Cyclin T1 antibody (ABIN7872934) specifically detects Cyclin T1 in WB 和 FACS. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7872934
发货至: 中国
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Quick Overview for Cyclin T1 抗体 (AA 253-281) (ABIN7872934)

抗原

See all Cyclin T1 (CCNT1) 抗体
Cyclin T1 (CCNT1)

适用

  • 56
  • 25
  • 15
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 50
  • 5
  • 1

克隆类型

  • 42
  • 14
多克隆

标记

  • 31
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
This Cyclin T1 antibody is un-conjugated

应用范围

  • 43
  • 19
  • 17
  • 16
  • 15
  • 12
  • 11
  • 7
  • 4
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS)
  • 抗原表位

    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 253-281

    原理

    CCNT1 Antibody / Cyclin T1

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 253-281 from the human protein was used as the immunogen for the CCNT1 antibody.

    亚型

    Ig Fraction
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the CCNT1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the CCNT1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Cyclin T1 (CCNT1)

    别名

    CCNT1

    背景

    CCNT1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin tightly associates with CDK9 kinase, and was found to be a major subunit of the transcription elongation factor p-TEFb. The kinase complex containing this cyclin and the elongation factor can interact with, and act as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and was shown to be both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner were also found to be involved in the phosphorylation and regulation of the carboxy-terminal domain (CTD) of the largest RNA polymerase II subunit.

    UniProt

    O60563
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