BRSK2 抗体 (AA 250-736)
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Quick Overview for BRSK2 抗体 (AA 250-736) (ABIN7872927)
抗原
See all BRSK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 250-736
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原理
- BRSK2 Antibody / Brain-selective kinase 2
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids M250-P736) was used as the immunogen for the BRSK2 antibody.
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亚型
- IgG
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anti-BR serine/threonine Kinase 2 (BRSK2) (Internal Region) antibody
Verified BRSK2 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-BR serine/threonine Kinase 2 (BRSK2) (AA 706-736), (C-Term) antibodyBRSK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB5548 unconjugated
anti-BR serine/threonine Kinase 2 (BRSK2) antibodyBRSK2 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BR serine/threonine Kinase 2 (BRSK2) (AA 1-170) antibodyBRSK2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-BR serine/threonine Kinase 2 (BRSK2) (AA 250-736) antibodyBRSK2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-BR serine/threonine Kinase 2 (BRSK2) (C-Term) antibodyBRSK2 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the BRSK2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the BRSK2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- BRSK2 (BR serine/threonine Kinase 2 (BRSK2))
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别名
- BRSK2
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背景
- BR serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the BRSK2 gene. BRSK2 was initially identified through a computer screen of the human genome and shows significant homology to the C. elegans neuronal cell polarity regulator SAD1. BRSK2 is expressed in the brain and to a lesser extent in the testes. BRSK2 is a member of the AMP-activated protein kinase subfamily and can be activated by the tumor suppressor kinase LKB1. More recently, it has been shown that both BRSK2 and the related protein BRSK1 are required for mammalian neuronal polarization. While BRSK1- and BRSK2-null mice were viable, double-mutant mice died within two hours of birth. Neurons from these mice showed uniformly-sized neurites as opposed to the normal long axon and multiple shorter dendrites. These neurites also displayed both axonal and dendritic markers. BRSK2 has also been shown to be an autoantigen in paraneoplastic limbic encephalitis. At least four isoforms of BRSK2 are known to exist.
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UniProt
- Q8IWQ3
抗原
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