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CDH6 抗体 (AA 250-450)

This 小鼠 单克隆 antibody specifically detects CDH6 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7872908
发货至: 中国
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Quick Overview for CDH6 抗体 (AA 250-450) (ABIN7872908)

抗原

See all CDH6 抗体
CDH6 (K-Cadherin (CDH6))

适用

  • 103
  • 22
  • 20
  • 4
  • 1

宿主

  • 82
  • 12
  • 9
  • 2
小鼠

克隆类型

  • 63
  • 37
  • 3
单克隆

标记

  • 55
  • 6
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CDH6 antibody is un-conjugated

应用范围

  • 78
  • 39
  • 37
  • 33
  • 12
  • 11
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

CDH6-3191
  • 抗原表位

    • 16
    • 9
    • 8
    • 7
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 250-450

    原理

    Cadherin 6 Antibody / CDH6 / K-Cadherin

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 250-450) from the human protein was used as the immunogen for the Cadherin 6 antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the Cadherin 6 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Cadherin 6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    CDH6 (K-Cadherin (CDH6))

    别名

    Cadherin 6

    背景

    This gene encodes a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion. This protein may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis.

    UniProt

    P55285

    途径

    Cell-Cell Junction Organization
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